“The Studio,” Seth Rogen’s Apple TV satire about Hollywood, is following one of Hollywood’s biggest trends — heading out of town.

Page Six has learned that a Season 2 episode of last year’s big Emmy Award winner will take place right here in New York, with one scene specifically set in Gallagher’s Steakhouse on W. 52nd Street.

During the first season of the dry-aged comedy series, the show had directors and actors — Martin Scorsese, Charlize Theron, Ron Howard, Ted Sarandos and more — play themselves to lend some on-the-lot authenticity. 

They’ve taken that true-to-life strategy eastward. So if the waiters and bartenders in the Gallagher’s sequence look straight out of central casting, that’s because they’re the real waiters and bartenders of Gallagher’s.   

Recently before the eatery opened, Rogen, who plays studio head honcho Matt Remick, and Ike Barinholtz, as VP Sal Saperstein, filmed a moment sitting at the 99-year-old Manhattan institution’s central bar. 

The duo discuss the death of Catherine O’Hara’s character Patty, the producer modeled after Sony Pictures’ Amy Pascal.  

O’Hara died in January at age 71 after a brief illness. 

The “Schitt’s Creek” actress was meant to appear in Season 2, which was actively filming at the time. But a source told the US Sun O’Hara never got to shoot her scenes.

“She was scheduled to film, but they reworked the schedule to focus on scenes without her character,” they said of the days when she was ill.

“Her death comes as a total shock to everyone on the show,” the source added. “She was the most beloved person on the set.”

In August, Rogen confirmed to The Times of London that they would be “acknowledging” O’Hara’s death in the plot.

“If anything, we’re acknowledging the idea that we are a little anchorless,” he said. 

“But, honestly, that is a part of life and what we all experience. And so while we try to not dwell too much on heavy themes in this show, they will be there in this second season. We are not ignoring it.”