A large apartment at Manhattan’s famed Dakota building is back on the market for $13.9 million — marking a staggering $25.1 million discount from its initial $39 million ask in 2016, Gimme Shelter has learned.

The sellers are Jane Rosenthal and Craig Hatkoff, who co-founded the Tribeca Film Festival with Robert De Niro in the aftermath of 9/11.

Rosenthal, who is De Niro’s producing partner and best known for films like “Meet the Parents,” “The Irishman,” and “Wag the Dog” — and Hatkoff, a real estate investor — divorced in 2014 after 19 years of marriage. It took them more than 30 years and 20 transactions to assemble the residence, which has more Central Park frontage than any other unit in the building, listing broker Ben Dixon, of Douglas Elliman, told Gimme Shelter.

The 6,000-square-foot apartment at 1 W. 72nd St. was the site of many entertainment industry and literary gatherings over the years. This sale includes a separate one-room, 400-square-foot unit across the hall that features three windows and a bath. It was asking $15 million last year. 

The Dakota is part of New Yorkers’ collective history. It’s where John Lennon was fatally shot by a crazed assassin in 1980. Yoko Ono still lives in a unit directly below this one. 

Past residents have also included the late Lauren Bacall, Roberta Flack, Judy Garland and Boris Karloff. 

The struggle to sell the unit may have to do with the difficulties facing co-op owners when it comes to making renovations inside landmarked, historic buildings, real estate brokers told Gimme Shelter. But the listing now comes with a floor plan created by Elena Frampton, of Frampton and Co., that was made after talks with the building’s architect, John Wender, Dixon said.

“I asked Elena to come up with the craziest plan to turn this residence on its head,” Dixon said. 

The changes include updating the residence to become a five-bedroom home with ensuite baths, Dixon said, adding all changes would still be subject to co-op board approval. 

“I think the big change is that we have more information on what you can do with the apartment. Before, it was presented as a finished product. Now we have an alternative floor plan so [potential buyers] with bigger budgets can create something with a more modern layout for today’s lifestyle,” Dixon said. 

The new floor plan also creates a great room that’s connected to a dining room and a parlor — with all 80 feet overlooking the park. 

“The great room is centered on the iconic triangle of the Dakota roofline,” Dixon said. 

He added that the apartment also contains original details, like shutters that date to 1885, along with original brass hinges, door knobs and woodwork. 

Design details also include 11-foot ceilings, coved archways and two woodburning fireplaces.

“Someone can create a very modern, livable layout — with historic charm and provenance,” Dixon said.