Gail Rudnick and Kim Murstein — the no-nonsense hosts of hit podcast series “Excuse My Grandma” — are The Post’s brand-new advice columnists.

From family feuds to friendship fallouts, money, marriage and sex, there’s no topic too taboo to tackle, and the native New Yorkers will hash out each issue from their differing perspectives to tell the tough-love truth — and you’ll thank them for it.

To get your questions answered, head to nypost.com/ema and drop them a note about what you need sorted.

Dear Excuse My Advice,

My friends are losing weight on GLP ones and boutique workouts I can’t afford, and the comparison is starting to mess with my head. How do I deal with this?

Grandma Gail: Don’t feel bad. Don’t compare yourself to your friends, for heaven’s sakes. You know, just wait. Wait a little bit. You’re going to get a pill for, like, $10. It’s going to do the same thing.

Kim: No! The advice should not be to also go on the GLP-1!

Kim: Here’s my thought. It’s less about the access to the drug and more about the comparison to people. Because I don’t know, there’s always something like, even if you get a skinny as them, maybe you’re going to start comparing the fact that they have long thick hair and you don’t. Whatever it is, how do you stop letting…

Grandma Gail: Social media get in your way.

Kim: Social media people, celebrities on TV, like, right. Mess with your own head. I don’t always have the answer as I do feel like I compare myself. I look at everybody and constantly I’m like, why am I not this? Why I’m not that. I think that’s just like, unfortunately, part of being a woman in, 2027, right?

Kim: I think it’s truly about the internal validation you give yourself. Always at any age. And I think that comes from finding happiness in other things like self-care, making you feel good. Maybe it’s watching reality TV, maybe it’s going to a theater with your friends. Finding something that is going to make you feel confident and stop comparing yourself. Okay, Grandma hates this answer, but I believe it.

Grandma Gail: I do hate the answer. She should stop comparing herself. She is her own person. Be comfortable in your own body and stop looking. This is this is very important. Stop looking at your friend. Nobody has it perfect. She probably is more messed up than than anybody, you know, but looks the way you like would like to look.

If it’s a weight issue, talk to your doctor, because there are things out there now that are less expensive than those shots were.

Dear Excuse My Advice,

My friend is in her 20s and she’s dating someone 20 years older than her. And every time we all hang out, something feels off. He’s polite, but the dynamic makes the group uncomfortable, and he’s constantly offering unsolicited life advice, because he’s more experienced. My friend insists he makes her feel comfortable, but he also talks very seriously about marriage, kids, and even retirement. And she just turned 25. Should I say something or is this not my place?

Grandma Gail: I don’t think it’s any of her business. I really think that that’s a thing between two people. They are in a relationship. If the friend is uncomfortable, then she should see the friend during the daytime or at a planned time when he’s not around. And keep it to a minimal. Because this is a thing between a man and woman who’ve already discussed this.

They know how different their ages are and they’re comfortable with it.

Kim: I kind of feel like the other option is she says to her friend who’s in the relationship — I love hanging out with you guys, but sometimes I feel like he’s giving me advice when I don’t ask for it.

No? You don’t like that?

Grandma Gail: I think you’re getting into somebody else’s relationship. You just have to deal with it and if you’re uncomfortable then you know what, just meet your friend for lunch when he’s not around.

Kim: Okay, what if she said a sort of passive aggressive comment, or she said a comment to him at the dinner, like, oh, you’re always trying to be my therapist?

Grandma Gail: No, I don’t think it’s nice and I don’t think it’s fair to their relationship. If she’s uncomfortable, then she just should move on and go with other friends. That’s it.

New York Post: How do you feel about age disparities?

Kim: The biggest age gap I would say to my friends, to go with is..

Grandma Gail: Ten years.

Kim: Yeah, ten. Even that’s a gap.

Grandma Gail: No, I like ten years.

Kim: I feel like the sweet spot is 3 to 5, with the guy being older because they’re immature more of the time.

Grandma Gail: Well, most of the time.