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High hantavirus levels found in rodents in parts of US — suggesting greater exposure risk: study
Fox News · 2026-05-22 · via New York Post

Researchers found unusually high hantavirus levels in rodents in the Pacific Northwest, suggesting greater exposure risk in the surrounding agricultural communities.

The area with the biggest prevalence is the Palouse region, which includes parts of eastern Washington and north-central Idaho in the Pacific Northwest.

Researchers from Washington State University’s College of Veterinary Medicine found unexpectedly high levels of Sin Nombre virus (SNV), which is the strain most strongly linked to hantavirus pulmonary syndrome (HPS) — among local rodent populations. 

In summer 2023, they collected samples from 189 deer mice, voles and chipmunks at eight farms and two forest sites.

Nearly 30% of sampled rodents showed evidence of prior exposure and about 10% had active infections, according to the study press release.

The rodents that tested positive were from both agricultural environments (farms) and natural settings (wilderness).

While deer mice are the primary carriers of hantavirus pulmonary syndrome, the researchers found infections across multiple rodent species.

Research scientist Robert Nofchissey preparing hantavirus research samples.

Research scientist Robert Nofchissey prepares samples of inactivated material as part of hantavirus research at the Center for Global Health at the University of New Mexico Health Sciences Center in Albuquerque, on May 4, 2026. AP

A young wild mouse sits on a pile of sunflower seeds.

Researchers found unusually high hantavirus levels in rodents in the Pacific Northwest, suggesting greater exposure risk in the surrounding agricultural communities. torook – stock.adobe.com

This suggests that Sin Nombre virus may be more widespread in the region than previously thought.

The findings were published in 2026 in Emerging Infectious Diseases, a peer-reviewed journal from the Centers for Disease Control and Prevention.

“We were surprised both by how common the virus was locally and by how little data existed for the Northwest,” said Stephanie Seifert, the study’s corresponding author and principal investigator of the Molecular Ecology of Zoonotic and Animal Pathogens lab in the College of Veterinary Medicine’s Paul G. Allen School for Global Health, in the press release. 

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“We’re really just beginning to understand how widespread and complex this virus is in rodent populations here.”

The Sin Nombre virus, the most common hantavirus in the US, is typically spread to humans through inhalation of aerosolized rodent urine, droppings or saliva and is not known to spread person-to-person.

This is different from the Andes virus, the strain linked to the recent outbreak on board the MV Hondius cruise ship.

The Andes virus is the only hantavirus that is capable of spreading between people through close, prolonged contact.

A pet rat with dark fur, white paws, and whiskers on a wooden surface.

The Sin Nombre virus, the most common hantavirus in the US, is typically spread to humans through inhalation of aerosolized rodent urine, droppings or saliva and is not known to spread person-to-person. George Dolgikh – stock.adobe.com

Dr. Sonja Bartolome, an expert in pulmonary and critical care at UT Southwestern Medical Center in Dallas, pointed out that since national tracking began in 1993, the illness has remained rare, with 864 cases reported between 1993 and 2022.

“Most cases have occurred in Colorado, New Mexico and Arizona, and 94% have been reported in states west of the Mississippi River,” Bartolome, who was not involved in the study, told Fox News Digital.

“It is important to conduct research that expands our understanding of how the virus spreads,” she went on.

Passengers wearing protective suits and ponchos board a bus after being evacuated from a cruise ship.

Passengers board a military bus after being evacuated from the hantavirus-stricken cruise ship MV Hondius at the industrial port of Granadilla de Abona, on the island of Tenerife in Spain’s Canary Islands, on May 10, 2026. AFP via Getty Images

“Studies like this – which obtain and compare viral genetic sequences across regions and animals – help clarify how the virus moves geographically and between species.”

Although similar findings have been reported in other regions, this is the first study to reveal the pattern in this part of the country, Bartolome noted.

“Because humans most commonly contract hantavirus through exposure to aerosolized rodent urine or droppings, precautions remain essential when cleaning areas with evidence of rodent activity,” she added.


Here’s the latest on the deadly hantavirus outbreak on the Dutch cruise ship:


The study presented some limitations, primarily that it only measured the infection in rodents and did not evaluate human transmission risk.

Additionally, the samples were only taken in the Palouse region and may not be generalized to all the Pacific Northwest.

The research was also conducted during a single season, which means the conclusions don’t reflect year-round data.

Aerial view of the cruise ship MV Hondius stationary off the port of Praia, Cape Verde.

This aerial picture shows a general view of the cruise ship MV Hondius stationary off the port of Praia, the capital of Cape Verde, on May 5, 2026. AFP via Getty Images

The study suggests the need for expanded hantavirus monitoring in the Pacific Northwest, especially in agricultural areas. 

The researchers recommend efforts to prevent rodent exposure for living and farming in rural areas.

Longer-term studies could help clarify how environmental conditions and seasonal changes affect the prevalence of the virus, they added.

“People may be exposed more often than we realize, but severe cases are more likely to be tested for hantavirus,” said Pilar Fernandez, a co-author on the study and a disease ecologist in the Allen School whose research focuses on the eco-epidemiology of zoonotic diseases, in the release.

“Understanding that gap — how exposure translates into disease — is the next big step.”