Over two dozen NYC-area hospitals earned strong patient safety grades in a new watchdog report card, while a few failed to make the mark.

Hospitals overseen by Catholic Health, Mount Sinai, NewYork-Presbyterian, Northwell Health and NYU Langone Health garnered “As” from the Leapfrog Group on Wednesday.

Over 2,300 US hospitals were rated “A” through “F” based on their protection of patients from preventable medical errors, accidents, injuries and healthcare-associated infections.

Some 450 facilities were not assigned a safety grade following a recent federal ruling that Leapfrog’s methodology is “deceptive and unfair.” Leapfrog is appealing the decision.

In a statement, NYU Langone Health noted that it’s among just 1% of hospitals nationwide to earn 12 consecutive “A” grades from Leapfrog.

Its “A” rating applies to Tisch Hospital and the Helen L. and Martin S. Kimmel Pavilion in Manhattan, NYU Langone Hospital — Brooklyn and NYU Langone Hospital — Long Island.

“Safe, high-quality care is the foundation of NYU Langone Health,” said Dr. Alec C. Kimmelman, dean and CEO of NYU Langone Health.

“Receiving an A grade from Leapfrog for the 12th consecutive time reflects the dedication of more than 54,000 people across our health system who put our patients first every day.”

For its part, Catholic Health lauded St. Francis Hospital & Heart Center on Long Island for earning its 17th consecutive and 27th overall “A” from Leapfrog, “the most of any hospital in New York State since the safety grading program launched in 2012.”

Three other Catholic Health hospitals achieved top marks.

In a statement, NewYork-Presbyterian highlighted its eight hospitals bestowed As, calling it “a testament to NewYork-Presbyterian’s commitment to providing the highest quality, compassionate care and the team’s expertise, training and dedication to putting patients’ safety first.”

Northwell Health has 15 A-rated hospitals in the Leapfrog report.

“Whether it’s through the federal government’s CMS Five-Star Quality ratings, US News and World Report’s Best Hospitals list or a host of other national comparisons, the quality and life-saving care being provided at Northwell hospitals repeatedly shines through,” said Dr. John D’Angelo, Northwell’s president and CEO. 

Across New York, 40 hospitals got “As.”

On the flip side, Leapfrog hit Brookdale Hospital Medical Center and Interfaith Medical Center in Brooklyn, Nassau University Medical Center on Long Island and St. John’s Episcopal Hospital in Queens with “D” grades. The Post reached out to reps for those facilities.

No New York hospitals flunked this time. The Leapfrog report card is released twice a year.