Interleague clubs kick off a three-game series on Monday night, as the reigning World Series champion Los Angeles Dodgers visit the Minnesota Twins at Target Field. 

The Dodgers (49–29, 1st NL West) are coming off back-to-back losses against the Orioles, looking to rebound against a Twins (38–41, 3rd AL Central) squad that has won six of its last seven games. And before he takes the mound for Wednesday’s series finale, two-way superstar Shohei Ohtani will look to stay hot at the dish and help put the Dodgers back in the win column. 

First pitch is at 7:40 p.m. ET. The Dodgers enter as 1.5-run road favorites with -156 moneyline odds on DraftKings Sportsbook. The Twins are +129 underdogs, with the game total set at O/U 10 runs.

Let’s dive into the top Shohei Ohtani prop bet for Monday’s series opener.

Best Shohei Ohtani Prop Bet for Dodgers vs. Twins

Best Bet: Shohei Ohtani 3+ Hits + Runs + RBIs (-127)

At the beginning of the season, it seemed that Shohei Ohtani was more focused on capturing an elusive Cy Young award than his fifth MVP. Now halfway through June, there’s a legitimate possibility that he takes home both. 

Ohtani, 31, rediscovered his generational swing sometime around May 6. Since then, the Japanese phenom is hitting .348 and leading the National League in on-base percentage (.452), wOBA (.468), OPS (1.111), and wRC+ (203). Ohtani has also crushed 10 of his 16 home runs and piled up 29 of his 43 RBIs during that stretch. 

The lefty slugger has gone deep six times over his last 12 games, including twice in his last four — each time reaching three combined hits, runs, and RBIs with one colossal swat. Ohtani looks primed for another strong day at the plate on Monday, facing struggling Twins hurler Zebby Matthews. 

The 26-year-old righty is liable for a 4.78 ERA (3.81 xERA) in seven starts this season, struggling to mitigate hard contact, generate chases, or keep the ball on the ground. Ohtani tends to capitalize against those sorts of things.