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Baltimore Orioles vs. New York Yankees prediction, pick for Friday 5/1/26
Cooper Alber · 2026-05-02 · via DraftKings Network

Cooper Albers previews Friday’s MLB game between the Baltimore Orioles and the New York Yankees at Yankee Stadium.

AL East rivals kick off a four-game set under the Friday night lights, as the New York Yankees host the Baltimore Orioles at Yankee Stadium. 

The Yankees (20–11, 1st AL East) return to the Bronx following an impressive 7–2 road trip, capped by a series victory over the Rangers in Texas. The Orioles (15–16, 3rd AL East) hit the road after splitting a six-game home stand against the Red Sox and Astros.

Looking at pitching probables, we’ve got Baltimore southpaw Cade Povich (1–0, 2.19 ERA) taking on New York right-hander Will Warren (3–0, 2.59 ERA).

First pitch is set for 7:05 p.m. ET. New York enters as a 1.5-run home favorite with -194 moneyline odds on DraftKings Sportsbook. Baltimore sits as a +159 underdog, with the total set at O/U 8.5 runs.

Orioles vs. Yankees Preview

Baltimore Orioles

Baltimore has gotten off to a decent start in 2026 — which is certainly an improvement from last season. After swinging big this winter for star slugger Pete Alonso, the Orioles rank 10th leaguewide in wRC+ (104), 9th in wOBA (.325), and 12th in runs scored (37) as the calendar flips to May. Their recent homestand seemingly sparked an offensive surge, with the club sitting around MLB’s top five in each of those metrics over the last seven days. 

But here’s the rub: the O’s pitching staff has been brutal — completely undone by injuries and poor batted-ball luck. Baltimore hopes to stem the tide Friday night when it hands the ball to lefty Cade Povich, who has performed well early on. The young starter has seemingly unlocked something in Year 3, posting a 2.19 ERA (3.64 xERA) with a 0.97 WHIP through his first two appearances. Granted, those outings came against the Pirates and Giants — and his career 5.02 ERA through 40 outings continues to raise a yellow flag.

New York Yankees

Want to hear something crazy? The Yankees’ offense currently sports the lowest BABIP in the American League (.265), underscoring some tough batted-ball luck early on. And yet, New York ranks fifth league-wide in wRC+ (109) and sixth in wOBA (.332), while also leading MLB with 48 home runs. The Bronx Bombers — bolstered by reigning MVP Aaron Judge and an ascendant Ben Rice — have essentially out-mashed their own bad luck. 

It’s not just a star-studded offense that has helped New York win 10 of its last 12 games and capture the top record in the AL. The Yankees also boast the hottest pitching staff in baseball, one that features multiple Cy Young candidates and paces the majors in ERA (3.11) and FIP (3.48). The starting rotation has been especially dominant, reinforced by a blistering start from young righty Will Warren. He has posted a 2.59 ERA (3.51 xERA) with a 1.15 WHIP and a 28.7% strikeout rate through his first six starts, helping him skirt some initial loud contact. Most recently, Warren yielded two earned runs over six innings against the Astros, racking up six strikeouts and just one walk in the process.

Orioles vs. Yankees Pick, Best Bet

While undoubtedly better than last season, the Orioles have played middling baseball so far without facing a good team. That’s not hyperbole. Their only opponent above .500 has been the 16–14 Diamondbacks, who wound up taking two of three contests in Baltimore in mid-April.

Meanwhile, the Yankees’ rotation is shaping up to be an all-timer once Gerrit Cole and Carlos Rodon return. But in the meantime, they’ll settle for the league’s most formidable starting five. Add to that a loaded lineup that’s yet to fully break out, and you’ve got the recipe for a statement home victory over a pedestrian division rival.

Best Bet: New York Yankees -1.5 Runs (+109)