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Cleveland Guardians vs. Washington Nationals prediction, pick for MLB on Monday 5/25/26
Dan Johnson · 2026-05-26 · via DraftKings Network

Dan Johnson takes you through his preview, prediction, and best bet for today’s baseball game between the Cleveland Guardians and the Washington Nationals.

Washington brings a better offensive résumé to Cleveland than the price might imply. The Nationals are 27-27, strong enough on the road at 17-11, and dangerous enough at the plate to make a heavy Guardians moneyline feel lazy at -180. They rank near the top of the league with a 108 wRC+, have already hit 65 HR, and come in with enough speed pressure to turn routine innings into long ones. Cleveland still owns the stronger full-team profile at 32-23, 15-10 at home, first in the AL Central and 8-2 over its last 10, but the shape of this game points more toward Guardians runs than a simple side. The Guardians have won eight of nine, just took a road series in Philadelphia, and now get a Washington staff that has been far more vulnerable than the Nationals’ record suggests. Below is my preview, prediction, and pick for today’s baseball game between the Cleveland Guardians and the Washington Nationals.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Guardians vs. Nationals prediction, preview

Zack Littell gives Cleveland the kind of matchup that can wake up a lineup before the bullpen door even opens. He enters at 3-4 with a 5.83 ERA, 1.45 WHIP and only 23 strikeouts, and the deeper indicators are even rougher: 7.46 xERA, 7.33 FIP, 5.67 xFIP, a 3.8% K-BB rate, 34.1% ground-ball rate and 83 Stuff+. The batted-ball profile is the bigger problem. Littell has allowed a .380 wOBA, .413 xwOBA, .442 xwOBAcon, 93.2 mph average exit velocity, 49.1% hard-hit rate, 13.6% barrel rate, 34.3% sweet-spot rate and a 20.3-degree average launch angle. That is a miserable recipe against a Cleveland order that can stack left-handed bats, switch-hitters and enough middle-order lift to make every walk feel dangerous.

Tanner Bibee gives the Guardians a much better starting-pitcher floor, even if Washington’s lineup keeps the run line from being automatic. Bibee is 0-6, but the record is misleading next to a 3.75 ERA, 1.25 WHIP, 52 strikeouts, 21 walks, 3.88 xERA, 3.97 FIP, 4.09 xFIP, 12.4% K-BB rate and 104 Stuff+. He has settled in with five quality starts over his last seven and a 2.59 ERA across that stretch, which matters against a Nationals team that can hit but still runs into empty stretches. The concern is contact: Bibee has allowed a .303 wOBA, .313 xwOBA, .356 xwOBAcon, 90.3 mph average exit velocity, 44.3% hard-hit rate and 7.4% barrel rate. James Wood and CJ Abrams can hurt those mistakes, so Washington scoring three or four runs is very much in play. That is also why Cleveland’s team total is cleaner than asking the Guardians to win by margin.

The Nationals’ lineup has real teeth at the top. Wood is already one of the scariest damage bats in the league with 13 HR, a .394-.395 wOBA range, .424 xwOBA, .520 wOBAcon, .580 xwOBAcon, 96.2 mph average exit velocity, 59.2% hard-hit rate, 25.8% barrel rate and 39.2% sweet-spot rate. Abrams gives Washington another pressure point with 11 doubles, two triples, 11 HR, 45 RBI and a .289 average, while Dylan Crews and Daylen Lile add enough athleticism behind them to keep Bibee from cruising on name value alone. Cleveland’s lineup is better built for this specific pitcher. Travis Bazzana leads off after a 3-for-4 game with a homer Sunday, bringing a .371 wOBA, .347 xwOBA, 13.0% walk rate and 17.0% strikeout rate. José Ramírez still owns a .373 xwOBA, 90.2 mph average exit velocity, 43.2% hard-hit rate and 8.3% barrel rate, Chase DeLauter is sitting on a .357 wOBA and .354 xwOBA, and the Hoskins-Manzardo pocket gives Cleveland enough lift to punish Littell when he misses up.

Nationals vs. Guardians pick, best bet

The market gives the best price on Cleveland’s offense, not Cleveland’s result. Guardians ML at -180 is too expensive against a Nationals team with a winning road record, a top-five offensive wRC+ and two left-handed stars who can change the score quickly. Guardians -1.5 at +123 is more attractive on payout, but Washington’s offense makes a 5-4 or 6-5 Cleveland win easy to picture. Full-game over 8 is live because both lineups have paths, though Bibee’s current form makes a Cleveland-specific angle more appealing. Guardians team total over 4.5 runs at -110 hits the cleanest part of the matchup: Littell’s hard contact, Cleveland’s confirmed top-half structure and a Washington bullpen sitting near the bottom of the league with a 4.77 ERA and 4.73 FIP. Cleveland can get there through Littell early or through a stressed bullpen late.

The miss case is straightforward: Littell finally keeps the ball on the ground, Ramírez and Bazzana fail to set traffic, and Bibee controls Washington well enough that Cleveland never has to press for add-on runs. The stronger read is that Littell’s 1.45 WHIP, low strikeout rate, elevated contact and Washington’s bullpen give the Guardians too many chances to reach five. Best bet: Guardians team total over 4.5 runs (-110), playable to -120.

Final score projection: Guardians 6, Nationals 3.

Best bet: Guardians TT o4.5 runs (-105) vs. Nationals

Tail it with me in the DKN Betting Group here!