A 15-game, 30-team MLB slate is on tap this Saturday. For those looking to cash in quickly on a bet, nothing makes more sense than an NRFI. With that being said, there’s more to this one than meets the eye. Some pitchers thrive early, while others take more time to get settled in than others. Which NRFI picks are worth a closer look today?

Ahead of Saturday’s MLB contests, here are three NRFI bets worth placing on DraftKings Sportsbook.

Guardians vs. Athletics NRFI (+115)

Sometimes, it literally pays to take a risk when it comes to NRFIs. That’s the case on Saturday, the second leg of a three-game series between the Guardians and A’s. The biggest hold up for most bettors is Sacramento’s Sutter Health Park, one of baseball’s ultimate hitter havens. Make no mistake: this venue is primed for scoring, taking the ball out with ease. Per Savant, Sutter Health was the second-friendliest environment for hitters in 2025. With that being said, that hasn’t led to instant offense for the home team this season. The Athletics rank 24th in baseball with a 21.43% YRFI rate at home.

For the visitors, it’ll be Slade Cecconi toeing the slab. Despite a solid second half last season, 2026 hasn’t been kind to the right-hander. Through six starts, he’s on the hook for a 6.23 ERA and 1.52 WHIP. Still, the 26-year-old has always been a good bet in the first inning. Through 46 career starts, Cecconi owns a stellar 82.6% NRFI rate. On the other side, it’ll be Jacob Lopez on the bump. Much like Cecconi, the fourth-year pro hasn’t maintained his momentum following a terrific second half. He’s posted a 5.84 ERA through six appearances in ’26. Regardless, the left-hander has a stellar 3.02 ERA at home over the last two seasons. Cleveland is averaging the sixth-fewest runs per game in baseball (3.97).

Giants vs. Rays NRFI (-150)

Tonight, it’ll be Landen Roupp taking the hill for San Francisco. The 27-year-old has impressed, notching a 2.55 ERA, 0.91 WHIP and 37 strikeouts over 35.1 innings of work. During each of his six outings so far, he has yet to surrender a first inning run. It’s also worth noting that Roupp has given up just one earned run over three starts on the road this season (0.50 ERA). Tampa Bay’s offense, while improved, often takes some time to get going. The Rays have a 25.81% YRFI rate, the 11th-worst mark in the league this season.

Taking the ball for the home team will be Griffin Jax, serving as Tampa Bay’s opener. The usually reliable reliever has been anything but that in 2026. Over 11.1 frames, the veteran has accounted for a dismal 6.35 ERA and 1.68 WHIP. Regardless, I’m willing to view this as a bump in the road for an otherwise quality reliever. During 17 career starts, Jax has surrendered a first inning run only twice (88%). It’s not as if today’s assignment is all too difficult. San Francisco’s offense is averaging an MLB-worst 3.25 runs per game this season. In addition, the Giants have a 12.50% YRFI rate on the road, fourth-worst in baseball.

Mets vs. Angels NRFI (-125)

The struggling Mets have been held back primarily by a lifeless offense this season. Pitching, while far from perfect, hasn’t been too shabby in Queens. That’s especially true when Nolan McLean steps on the rubber. The rookie, enjoying his first full MLB campaign, is already one of the sport’s most exciting arms. Through 35.1 innings in 2026, the right-hander has recorded a 2.55 ERA, 0.85 WHIP and 45 strikeouts. Los Angeles wields an above-average, power-hitting lineup. However, the Angels are much better on the road; their 3.38 runs per game at home rank 27th in the league.

For the Halos, it’ll be Reid Detmers on the mound tonight. The southpaw, while capable (4.28 ERA), is far from consistent. Fortunately for him, the Mets might be the easiest assignment in the sport for opposing pitchers. New York is averaging a National League-worst 3.21 runs per game on the road. The Amazins have also produced baseball’s fourth-lowest OPS against left-handed pitching (.631). Detmers has given up a first inning run once over six starts (83.3%).