The Athletics and Orioles play the second game of their three-game series on Saturday, May 9.

Baltimore is a -136 moneyline favorite, while the Athletics are +113 on DraftKings Sportsbook. The game total is set at over/under 9.5 runs.

Let’s get into a pick and prediction for this Athletics vs. Orioles game.

Athletics vs. Orioles prediction, preview

The Orioles had a busy offseason but are off to a weak start to the 2026 season. They’ve lost seven of their last nine, including the series opener against the Athletics. Saturday is the second game of this series with Shane Baz and Aaron Civale on the mound.

Baz is in his first season with the Orioles, but he hasn’t found his footing just yet. His last start was 5.2 innings in which he allowed five earned runs, five hits and five walks against the Yankees. Sure, New York is a difficult matchup, but he’s allowed at least four earned runs in four of seven starts this season.

The Athletics are a middle-of-the-pack offense, averaging the 15th most runs per game in the majors. They won the first game of the series 4-3 with Nick Kurtz hitting 2-5 with two RBI. The lineup can get hot at times, which is dangerous for a struggling pitcher like Baz.

Civale is a veteran right-hander, who is in his first season with the Athletics. He’s never been an ace, but he’s had quality seasons with different teams. Through seven starts in 2026, he holds a 2.95 ERA with a 27-10 strikeout to walk ratio. His last two starts have been excellent, allowing just one earned run across 11.0 innings.

Baltimore’s offense ranks 11th in runs per game, but it meets a red hot Civale on Saturday. Pete Alonso will need to continue his nine-game hit streak for the Orioles to get a win.

Athletics vs. Orioles Pick, Best Bet

Civale isn’t an ace, but he’s been great this season. On the other hand, Baz can’t slow down offenses. The Athletics should have a field day on the road.

Best Bet: Athletics ML (+113)