American League squads wrap their four-game series Sunday afternoon, as the Minnesota Twins host the Toronto Blue Jays at Target Field.

The Blue Jays (16–17, 3rd AL East) have taken two of the first three matchups — capped by Saturday’s 11–4 drubbing — and have won six of their last eight games. The Twins (14–20, 4th AL Central) have dropped 13 of their last 16 contests and look to avoid their fifth straight series loss. They did steal two of three games in Toronto earlier this season, though.

Looking at the pitching probables, we’ve got breakout Toronto right-hander Trey Yesavage (1–0, 0.00 ERA) taking on star Minnesota righty Joe Ryan (2–3, 3.76 ERA).

First pitch is tabbed for 12:35 p.m. ET. Minnesota enters as a slight -112 favorite on DraftKings Sportsbook, while Toronto sits at -108 on the moneyline. The total is set at O/U eight runs.

Blue Jays vs. Twins Preview

Toronto Blue Jays

Toronto’s small-ball approach — a strategy that fueled its first World Series appearance in over three decades — has failed to replicate the same success in 2026. While still refusing to strike out, the Blue Jays rank near MLB’s bottom in OPS (24th), wRC+ (24th), wOBA (25th), and runs scored (25th). Superstar slugger Vladimir Guerrero Jr. is the only everyday starter with an OPS north of .810. 

Although the pitching staff has also struggled early on, the Blue Jays recently welcomed back burgeoning ace Trey Yesavage — who has picked up right where he left off, following an October breakout. The club’s top prospect, armed with a wicked splitter, delivered 5.1 shutout innings in his first start of the season against the Red Sox. Behind him is arguably the unluckiest bullpen in all of baseball, one that ranks third in xERA (3.30) and third-to-last in BABIP (.324).

Minnesota Twins

While the bats have cooled amid their nosedive, the Twins have showcased a pretty solid offense heading into May. Minnesota ranks 17th league-wide in OPS (.708), 14th in wRC+ (99), and 12th in wOBA (.320), while also sitting in the sport’s top ten for runs scored (157), home runs (39), and stolen bases (26). Star center fielder Byron Buxton remains the centerpiece of the order, boasting an .857 OPS with 10 home runs through 31 games. 

Still, the Twins have struggled to provide run support for ace Joe Ryan, winning just two of the seven games he’s started so far. It hasn’t helped that the former All-Star, 29, has already endured a pair of blowup starts — though he still owns a respectable 3.76 ERA (3.11 xERA) and a 1.04 WHIP with 39 strikeouts through his first 38.1 innings of work. Ryan is coming off a solid performance against the Mariners, holding them to two earned runs over six frames with six strikeouts. He’ll look to provide length for the Twins to keep their dreadful bullpen — liable for the fourth-worst ERA in the majors (5.03) — as far away from the action as possible.

Blue Jays vs. Twins Pick, Best Bet

This one has “pitching duel” written all over it — a proven ace pitted against a budding superstar. Considering that neither club has truly wowed with their bats, count on a low-scoring affair in Sunday’s series finale. 

Best Bet: Under 8 Runs (-115)