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Chicago Cubs vs. Milwaukee Brewers prediction, pick for MLB on Monday 5/18/26
Dan Johnson · 2026-05-19 · via DraftKings Network

Dan Johnson takes you through his preview, prediction, and best bet for today’s baseball game between the Chicago Cubs and the Milwaukee Brewers.

Milwaukee and Chicago get their first look at each other since last year’s NLDS, when the Brewers squeezed out a 3-2 series win and kept the Cubs sitting with that familiar October itch all winter. Now they arrive at Wrigley Field with the NL Central already humming: Chicago is 29-18, first in the division, 18-5 at home and riding a 15-game home winning streak, while Milwaukee is 26-18, just 1.5 games back, 8-2 over its last 10 and still carrying the muscle memory of seven straight full seasons finishing ahead of the Cubs. The all-time series is basically a coin flip, Milwaukee ahead 230-226, with Chicago up 119-110 at Wrigley and the run differential nearly dead even. Add Craig Counsell, Pat Murphy, last year’s playoff bruise and Wrigley showing wind out to center, and this plays like a May game with teeth. Below is my preview, prediction, and pick for today’s baseball game between the Chicago Cubs and the Milwaukee Brewers.

Here’s how I’ll play it. I’ll be pumping out these predictions for individual games all season, with plenty of coverage here on DraftKings Network. Follow my handle @dansby_edits for more betting plays.

Cubs vs. Brewers prediction, preview

Brandon Sproat is the game’s first real stress point. The rookie right-hander has a 5.75 ERA, 1.53 WHIP, 36 strikeouts, 20 walks and eight homers allowed in 36 innings, with a contact profile that looks dangerous in this park: .380 wOBA allowed, .345 xwOBA, .452 wOBAcon, 88.8 mph average exit velocity, 40.2% hard-hit rate, 9.3% barrel rate and a 15.7-degree average launch angle. The left-handed split is the pressure lane. Lefties have tagged him for 16 hits, four homers and 14 walks in 15.1 innings, good for a 1.96 WHIP, and that pairs poorly with his pitch-level leakage: .421 wOBA on the sinker, .370 on the cutter, .438 on the curveball and .445 on the changeup. Shota Imanaga gives Chicago the steadier half of the pitching matchup with a 4-3 record, 2.32 ERA, 0.90 WHIP, 2.84 FIP and 59 strikeouts against 13 walks in 54.1 innings. He has allowed two earned runs or fewer in seven of his last eight starts, which is why the broader run environment still tilts more cleanly through Chicago’s bats than through a full-game shootout.

The Cubs’ lineup is built to make Sproat uncomfortable. Chicago is fourth in MLB in OPS at .749, fourth in runs, owns 57 homers, and has been strong against right-handed pitching at .238/.334/.405 with a .739 OPS, 42 homers and 155 walks. The projected order gives the matchup real shape: Nico Hoerner setting the table, Moisés Ballesteros giving an immediate left-handed look, Alex Bregman in a premium traffic spot, Ian Happ and Michael Busch attacking Sproat’s lefty issues, Seiya Suzuki adding right-handed thump, and Pete Crow-Armstrong/Dansby Swanson extending the bottom third. Suzuki is sitting around a .369 wOBA, .350 xwOBA, 41.0% hard-hit rate and 8.4% barrel rate. Crow-Armstrong adds 90.8 mph average exit velocity, 45.2% hard-hit and 8.1% barrel. Bregman enters hot, hitting .385/.429/.538 over his last six games during an eight-game hitting streak. This is lineup length, split fit and weather working together.

Brewers vs. Cubs pick, best bet

Milwaukee’s offense keeps the full-game total alive, but Imanaga makes that path less direct. The Brewers are scoring 5.0 runs per game, have 49 steals, and bring a top of the order that can pressure with Jackson Chourio, Brice Turang and William Contreras before Gary Sánchez and Andrew Vaughn supply the heavier swings. Their current form is legitimate: 43 runs over the last 10 games while allowing only 24. The issue is how they score against left-handed pitching. Milwaukee is last in MLB in home runs overall, and the lefty split has been a drag at .209/.308/.294 with a .602 OPS. That is a tough ask against Imanaga’s command, home-run suppression and ability to keep the ball off barrels often enough to avoid crooked innings. Milwaukee can run, grind and use the wind if Imanaga misses, but the matchup asks the Brewers to string together traffic rather than lean on their easiest power lane.

That market split is why the bet shape matters. Full-game over 10.5 has weather support, but it asks Milwaukee to do enough against Imanaga for the game to clear a big number. Cubs -1.5 at plus money is tempting, but it brings Chicago’s bullpen into a margin script against a Brewers team that has lived in close-game pressure for years. Cubs F5 team total over 3.5 at plus money has logic because it attacks Sproat before Milwaukee’s rested bullpen can steady the game, though four runs in five innings is still a demanding window. The full-game Cubs team total keeps the best parts of the handicap: Sproat’s walk and homer profile, his left-handed split, Chicago’s top-eight offense against righties, the projected lineup’s balance, and Wrigley wind carrying the ball for all nine innings.

Best bet: Cubs team total over 5.5 runs -115. Playable to -125 if the wind stays out and the projected Cubs core holds. The clean way it loses is Sproat finding enough strike-throwing rhythm to survive the lefty pocket, Milwaukee’s rested bullpen cutting off the middle innings, and Chicago stranding traffic instead of turning walks into crooked numbers. The better read is that Sproat’s command, elevated contact, left-handed damage lane and eight homers allowed in 36 innings give the Cubs too many ways to reach six in wind-out Wrigley.

Final score projection: Cubs 7, Brewers 4.

Best bet: Cubs TT o5.5 runs (-115) vs. Brewers

Tail it with me in the DKN Betting Group here!