Indeed, and with inline script metadata, for example: #! /usr/bin/python3 # /// script # requires-python = ">=3.12" # dependencies = [ # "rich-argparse", # ] # /// from rich_argparse import RichHelpFormatter import sys ... bash $ uv run myscript.py Can also go one step further with a shebang trick and do: bash$ cat myscript #! /usr/bin/env uv run myscript # /// script # requires-python = ">=3.12" # dependencies = [ # "rich-argparse", # ] # /// from rich_argparse import RichHelpFormatter import sys ... bash$ chmod 0755 myscript bash$ ./myscript