MOUNTAINAIR, N.M. (AP) — Three people are dead and more than a dozen first responders had to be quarantined and assessed Wednesday for possible exposure to an unidentified substance after being called to a suspected drug overdose at a rural New Mexico home, authorities said.

New Mexico State Police said three of the four people found unresponsive inside the home east of Albuquerque died. The fourth was being treated at a hospital in Albuquerque.

During the response, authorities said, first responders were exposed to the substance and began experiencing symptoms including nausea and dizziness.

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Officials at University of New Mexico Hospital confirmed that 23 patients who were exposed to an unknown substance were assessed and decontaminated after being transported to the hospital. Most of those were first responders who were showing no symptoms and were later discharged.

Medical teams continued to monitor three symptomatic patients Wednesday evening, according to the hospital.

Two first responders were listed in serious condition, said Officer Wilson Silver with New Mexico State Police.

Mountainair EMS Chief Josh Lewis, who was the first to enter the residence, was hospitalized overnight for observation, Mountainair Mayor Peter Nieto said in a social media post.

Also among those experiencing symptoms were EMTs from Torrance County and nurses from the University of New Mexico hospital who came into contact with individuals on scene, he said. The mayor added that public works crew had confirmed that the health issues were not related to carbon monoxide or natural gas exposure.

Albuquerque Fire Rescue Hazmat teams were assisting at the scene in Mountainair, a rural community east of Albuquerque, in efforts to identify the substance involved.

"At this time, investigators believe the substance may be transmitted through contact and do not believe it to be airborne," Silver said.

As law enforcement officers from multiple agencies remained on the scene late Tuesday afternoon, three bodies were placed onto gurneys and then loaded into a white van and driven away.

Yellow police tape surrounded the home, located on a dirt road in a rural subdivision. A singlewide trailer could be seen in the home's backyard, with several cars, trucks and vans in the driveway.

While the investigation was ongoing, Silver said indications were pointing toward drugs as a possible factor in the deaths. He added that there was no threat to the public.

Residents, however, took to social media to voice their frustrations about drug use in the community and elsewhere.

The mayor said the town's law enforcement officers and first responders work every day to protect the community and respond to difficult situations.

"But the reality is that addiction and substance abuse are issues affecting communities all across our state and nation," Nieto said. "There is no simple or immediate solution. Lasting change requires family support, accountability, education, and most importantly, individuals who are willing to accept help."

Montoya Bryan reported from Albuquerque, New Mexico.