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The firms are developing a range of approaches – from autologous cell therapies made from a patient’s own cells and ready-made cell products to gene therapies and non-invasive ultrasounds – although many of these candidates are still in early-stage trials.
Many patients with Parkinson’s disease need to take levodopa – a drug first developed in the 1960s – and other medications that alleviate the symptoms but do not halt the disease’s progression, and whose effectiveness diminishes over time, according to the American Parkinson Disease Association and a 2025 study by the Parkinson’s Foundation.
Now Chinese drug makers are making breakthroughs, clearing significant regulatory and clinical hurdles.
The latest example is Shanghai start-up UniXell Biotechnology, which received clinical trial approval in China in 2024 and the US in 2025 for UX‑DA001, an autologous stem cell therapy that uses a patient’s own cells to replace the dopamine‑producing neurons destroyed by Parkinson’s disease.
Founded in 2021, UniXell has raised more than 300 million yuan (US$44 million) from A and A-plus financing rounds that drew support from state-backed funds, venture capital and pharmaceutical investor Tasly Pharmaceutical, the company announced in February.
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