We study infinite-horizon Discounted Markov Decision Processes (DMDPs) under a generative model. Motivated by the Algorithm with Advice framework Mitzenmacher and Vassilvitskii 2022, we propose a novel framework to investigate how a prediction on the transition matrix can enhance the sample efficiency in solving DMDPs and improve sample complexity bounds. We focus on the DMDPs with $N$ state-action pairs and discounted factor $γ$. Firstly, we provide an impossibility result that, without prior knowledge of the prediction accuracy, no sampling policy can compute an $ε$-optimal policy with a sample complexity bound better than $\tilde{O}((1-γ)^{-3} Nε^{-2})$, which matches the state-of-the-art minimax sample complexity bound with no prediction. In complement, we propose an algorithm based on minimax optimization techniques that leverages the prediction on the transition matrix. Our algorithm achieves a sample complexity bound depending on the prediction error, and the bound is uniformly better than $\tilde{O}((1-γ)^{-4} N ε^{-2})$, the previous best result derived from convex optimization methods. These theoretical findings are further supported by our numerical experiments.