This paper proposes a two-stage pseudo anomaly-guided anomaly detection method (\textbf{T}wo-stage \textbf{P}seudo \textbf{A}nomaly-guided \textbf{A}nomaly \textbf{D}etection, \textbf{TPA-AD}) for axle-box bearing time-series anomaly detection (time series anomaly detection, TSAD) under the setting where only normal samples are available for training. The method first generates pseudo-anomalous windows near the normal boundary using a reconstruction model and per-feature target-error control. It then learns anomaly-sensitive representations through contrastive learning between normal and pseudo-anomalous windows, and finally produces window-level and point-level anomaly scores using k-nearest neighbors (KNN). Compared with existing methods that rely on known fault categories, real anomaly priors, or random anomaly injection, TPA-AD improves the separability of the normal boundary by constructing pseudo-anomalies in boundary neighborhoods and can jointly handle continuous and discrete features in mixed-variable scenarios. The main experiments are conducted on bearing fault detection datasets and degradation-process datasets, with an additional exploratory extension on $13$ public TSAD datasets. The results show that the proposed method yields relatively stable anomaly responses, is sensitive to degradation evolution, and demonstrates a certain degree of broader applicability on public TSAD benchmarks and real high-speed-train-related bearing data.