While it is well-known how to compute the cells of a Laguerre tessellation for a given set of weighted generator points, it is not obvious how to invert a Laguerre tessellation. That is, given that one observes a Laguerre tessellation, how can one retrieve the weighted generators corresponding to the observed cells. In this paper, we consider inversion of a class of random Laguerre tessellations known as Poisson-Laguerre tessellations. The weighted generators of observed cells of a Poisson-Laguerre tessellation are of interest because knowledge of these weighted generators is useful for statistical inference of Poisson-Laguerre tessellations. For general Laguerre tessellations we provide a characterization of all configurations of weighted generator points which yield the same Laguerre tessellation. For Poisson-Laguerre tessellations we propose a method for consistent inversion, meaning that as one observes the tessellation through increasing observation windows, a closer approximation of the original weighted generators can be obtained. In a simulation study we examine both performance of the inversion procedure, as well as the use of the obtained approximated weighted generators for nonparametrically estimating the weight distribution function corresponding to a Poisson-Laguerre tessellation.