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Calibeating for general proper losses: A Bregman divergence approach Dimension-Free Convergence of Discrete Diffusion Models: Adjoint Equations Induce the Right Space XAI and Statistical Analysis for Reliable Intrusion Detection in the UAVIDS-2025 Dataset: From Tree to Hybrid and Tabular DNN Ensembles Reasoning Models Don't Just Think Longer, They Move Differently TabPFN-3: Technical Report Reframing preprocessing selection as model-internal calibration in near-infrared spectroscopy: A large-scale benchmark of operator-adaptive PLS and Ridge models Towards a holistic understanding of Selection Bias for Causal Effect Identification Adaptive Kernel Density Estimation with Pre-training Coreset-Induced Conditional Velocity Flow Matching RISED: A Pre-Deployment Evaluation Framework for High-Stakes AI Decision-Support Systems, with Application to Healthcare ISOMORPH: A Supply Chain Digital Twin for Simulation, Dataset Generation, and Forecasting Benchmarks Yield Curves Dynamics Using Variational Autoencoders Under No-arbitrage Model-based Bootstrap of Controlled Markov Chains Online Learning-to-Defer with Varying Experts Self-Supervised Laplace Approximation for Bayesian Uncertainty Quantification Keeping Score: Efficiency Improvements in Neural Likelihood Surrogate Training via Score-Augmented Loss Functions One-Step Generative Modeling via Wasserstein Gradient Flows Exact Stiefel Optimization for Probabilistic PLS: Closed-Form Updates, Error Bounds, and Calibrated Uncertainty A Composite Activation Function for Learning Stable Binary Representations Adaptive Calibration in Non-Stationary Environments Real vs. Semi-Simulated: Rethinking Evaluation for Treatment Effect Estimation Federated Language Models Under Bandwidth Budgets: Distillation Rates and Conformal Coverage On Variance Reduction in Learning Mean Flows When Attention Beats Fourier: Multi-Scale Transformers for PDE Solving on Irregular Domains A Refined Generalization Analysis for Extreme Multi-class Supervised Contrastive Representation Learning Ensemble Distributionally Robust Bayesian Optimisation The Proxy Presumption: From Semantic Embeddings to Valid Social Measures Modulated learning for private and distributed regression with just a single sample per client device Query-efficient model evaluation using cached responses Order-Agnostic Autoregressive Modelling with Missing Data Grokking or Glitching? 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Testing for Single-Population Ancestry in the Admixture Model
Holger Dette, Carola Sophia Heinzel, Zoe Lange, Peter Pfaffelhub · 2026-06-01 · via stat updates on arXiv.org

The Admixture Model describes genetic marker data by representing each individual's genome as a mixture of contributions from $K$ ancestral populations, with the individual admixture vector summarizing the corresponding ancestry proportions. In population and forensic genetics, a key question is whether an individual's genome supports a predominantly single-ancestry interpretation or whether an admixed interpretation is more appropriate. We propose a statistical test for single-population ancestry in the supervised Admixture Model, where ancestral allele frequencies are treated as known. The test assesses whether the largest admixture component exceeds a practitioner-chosen dominance threshold, giving precise meaning to the notion of a sufficiently strong single-population contribution. To calibrate the test, we develop a constrained parametric bootstrap procedure that generates data under a null-constrained maximum likelihood estimator, accounting for the constrained hypothesis structure, the marker-wise heterogeneity and small sample sizes. Under standard regularity conditions, we prove that the proposed test has asymptotic level $α$ and is consistent, ensuring control of false single-ancestry declarations while reliably detecting dominant ancestry components. Simulation studies demonstrate good finite-sample performance across different numbers of ancestral populations, marker-panel sizes, dominance thresholds, and allele-frequency distributions. We further illustrate the practical utility of the method using data from the 1000 Genomes Project. The proposed framework delivers interpretable, threshold-based ancestry assessment with rigorous error control, and extends constrained bootstrap methodology to the independent but non-identically distributed setting of genetic marker data.