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ClawGUI: A Unified Framework for Training, Evaluating, and Deploying GUI Agents On the Robustness of Watermarking for Autoregressive Image Generation Revisiting Compositionality in Dual-Encoder Vision-Language Models: The Role of Inference Anthropogenic Regional Adaptation in Multimodal Vision-Language Model From Redaction to Restoration: Deep Learning for Medical Image Anonymization and Reconstruction The Salami Slicing Threat: Exploiting Cumulative Risks in LLM Systems BoxTuning: Directly Injecting the Object Box for Multimodal Model Fine-Tuning Semantic-Geometric Dual Compression: Training-Free Visual Token Reduction for Ultra-High-Resolution Remote Sensing Understanding Lightweight Low-Light Image Enhancement via Distribution-Normalizing Preprocessing and Depthwise U-Net Back to the Barn with LLAMAs: Evolving Pretrained LLM Backbones in Finetuning Vision Language Models Pseudo-Unification: Entropy Probing Reveals Divergent Information Patterns in Unified Multimodal Models QShield: Securing Neural Networks Against Adversarial Attacks using Quantum Circuits Evaluating the Impact of Medical Image Reconstruction on Downstream AI Fairness and Performance Retinal Cyst Detection from Optical Coherence Tomography Images LoViF 2026 The First Challenge on Weather Removal in Videos STORM: End-to-End Referring Multi-Object Tracking in Videos Data-Efficient Surgical Phase Segmentation in Small-Incision Cataract Surgery: A Controlled Study of Vision Foundation Models Rethinking the Diffusion Model from a Langevin Perspective Zero-shot World Models Are Developmentally Efficient Learners Edu-MMBias: A Three-Tier Multimodal Benchmark for Auditing Social Bias in Vision-Language Models under Educational Contexts VGA-Bench: A Unified Benchmark and Multi-Model Framework for Video Aesthetics and Generation Quality Evaluation Degradation-Consistent Paired Training for Robust AI-Generated Image Detection FREE-Switch: Frequency-based Dynamic LoRA Switch for Style Transfer Demographic and Linguistic Bias Evaluation in Omnimodal Language Models FlowPalm: Optical Flow Driven Non-Rigid Deformation for Geometrically Diverse Palmprint Generation Cross-Cultural Value Awareness in Large Vision-Language Models I Walk the Line: Examining the Role of Gestalt Continuity in Object Binding for Vision Transformers GLEaN: A Text-to-image Bias Detection Approach for Public Comprehension From UAV Imagery to Agronomic Reasoning: A Multimodal LLM Benchmark for Plant Phenotyping Not Your Stereo-Typical Estimator: Combining Vision and Language for Volume Perception
A WDLoRA-Based Multimodal Generative Framework for Clinic...
Xin Zhang, Liangxiu Han, Tam Sobeih, Yue Shi, Yalin Zheng, Uazma · 2026-02-14 · via cs.CV updates on arXiv.org

Corneal Confocal Microscopy (CCM) is a sensitive tool for assessing small-fiber damage in Diabetic Peripheral Neuropathy (DPN), yet the development of robust, automated deep learning-based diagnostic models is limited by scarce labelled data and fine-grained variability in corneal nerve morphology. Although Artificial Intelligence (AI)-driven foundation generative models excel at natural image synthesis, they often struggle in medical imaging due to limited domain-specific training, compromising the anatomical fidelity required for clinical analysis. To overcome these limitations, we propose a Weight-Decomposed Low-Rank Adaptation (WDLoRA)-based multimodal generative framework for clinically guided CCM image synthesis. WDLoRA is a parameter-efficient fine-tuning (PEFT) mechanism that decouples magnitude and directional weight updates, enabling foundation generative models to independently learn the orientation (nerve topology) and intensity (stromal contrast) required for medical realism. By jointly conditioning on nerve segmentation masks and disease-specific clinical prompts, the model synthesises anatomically coherent images across the DPN spectrum (Control, T1NoDPN, T1DPN). A comprehensive three-pillar evaluation demonstrates that the proposed framework achieves state-of-the-art visual fidelity (Fréchet Inception Distance (FID): 5.18) and structural integrity (Structural Similarity Index Measure (SSIM): 0.630), significantly outperforming GAN and standard diffusion baselines. Crucially, the synthetic images preserve gold-standard clinical biomarkers and are statistically equivalent to real patient data. When used to train automated diagnostic models, the synthetic dataset improves downstream diagnostic accuracy by 2.1% and segmentation performance by 2.2%, validating the framework's potential to alleviate data bottlenecks in medical AI.