The paper presents and comparatively analyses several deep learning approaches to automatically detect tuberculosis related lesions in lung CTs, in the context of the ImageClef 2020 Tuberculosis task. Three classes of methods, different with respect to the way the volumetric data is given as input to neural network-based classifiers are discussed and evaluated. All these come with a rich experimental analysis comprising a variety of neural network architectures, various segmentation algorithms and data augmentation schemes. The reported work belongs to the SenticLab.UAIC team, which obtained the best results in the competition.