Optical Music Recognition (OMR) is a cornerstone of music digitization initiatives in cultural heritage, yet it remains limited by the scarcity of annotated data and the complexity of historical manuscripts. In this paper, we present a preliminary study of Active Learning (AL) and Sequential Learning (SL) tailored for object detection and layout recognition in an old medieval music manuscript. Leveraging YOLOv8, our system selects samples with the highest uncertainty (lowest prediction confidence) for iterative labeling and retraining. Our approach starts with a single annotated image and successfully boosts performance while minimizing manual labeling. Experimental results indicate that comparable accuracy to fully supervised training can be achieved with significantly fewer labeled examples. We test the methodology as a preliminary investigation on a novel dataset offered to the community by the Anonymous project, which studies laude, a poetical-musical genre spread across Italy during the 12th-16th Century. We show that in the manuscript at-hand, uncertainty-based AL is not effective and advocates for more usable methods in data-scarcity scenarios.