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ClawGUI: A Unified Framework for Training, Evaluating, and Deploying GUI Agents On the Robustness of Watermarking for Autoregressive Image Generation Revisiting Compositionality in Dual-Encoder Vision-Language Models: The Role of Inference Anthropogenic Regional Adaptation in Multimodal Vision-Language Model From Redaction to Restoration: Deep Learning for Medical Image Anonymization and Reconstruction The Salami Slicing Threat: Exploiting Cumulative Risks in LLM Systems BoxTuning: Directly Injecting the Object Box for Multimodal Model Fine-Tuning Semantic-Geometric Dual Compression: Training-Free Visual Token Reduction for Ultra-High-Resolution Remote Sensing Understanding Lightweight Low-Light Image Enhancement via Distribution-Normalizing Preprocessing and Depthwise U-Net Back to the Barn with LLAMAs: Evolving Pretrained LLM Backbones in Finetuning Vision Language Models Pseudo-Unification: Entropy Probing Reveals Divergent Information Patterns in Unified Multimodal Models QShield: Securing Neural Networks Against Adversarial Attacks using Quantum Circuits Evaluating the Impact of Medical Image Reconstruction on Downstream AI Fairness and Performance Retinal Cyst Detection from Optical Coherence Tomography Images LoViF 2026 The First Challenge on Weather Removal in Videos STORM: End-to-End Referring Multi-Object Tracking in Videos Data-Efficient Surgical Phase Segmentation in Small-Incision Cataract Surgery: A Controlled Study of Vision Foundation Models Rethinking the Diffusion Model from a Langevin Perspective Zero-shot World Models Are Developmentally Efficient Learners Edu-MMBias: A Three-Tier Multimodal Benchmark for Auditing Social Bias in Vision-Language Models under Educational Contexts VGA-Bench: A Unified Benchmark and Multi-Model Framework for Video Aesthetics and Generation Quality Evaluation Degradation-Consistent Paired Training for Robust AI-Generated Image Detection FREE-Switch: Frequency-based Dynamic LoRA Switch for Style Transfer Demographic and Linguistic Bias Evaluation in Omnimodal Language Models FlowPalm: Optical Flow Driven Non-Rigid Deformation for Geometrically Diverse Palmprint Generation Cross-Cultural Value Awareness in Large Vision-Language Models I Walk the Line: Examining the Role of Gestalt Continuity in Object Binding for Vision Transformers GLEaN: A Text-to-image Bias Detection Approach for Public Comprehension From UAV Imagery to Agronomic Reasoning: A Multimodal LLM Benchmark for Plant Phenotyping Not Your Stereo-Typical Estimator: Combining Vision and Language for Volume Perception
IMPLICITSTAINER: Resolution Agnostic Data-Efficient Virtu...
Tushar Kataria, Beatrice Knudsen, Shireen Y. Elhabian · 2025-05-15 · via cs.CV updates on arXiv.org

Hematoxylin and eosin (H&E)-stained slides are central to cancer diagnosis and monitoring, visualizing tissue architecture and cellular morphology. However, H&E lacks the molecular specificity needed to distinguish cell states and functional activation. Antibody-based stains, such as immunohistochemistry (IHC), are therefore required to identify specific phenotypes (e.g., CD3$^+$ T cells or HER2-positive tumor cells) but are costly, time-consuming, and not universally available. Deep learning-based image translation methods, often termed virtual staining, offer a complementary alternative by generating virtual immunostains directly from H&E images. Most existing virtual staining methods are patch-based and operate at fixed resolutions, often requiring large datasets and additional post-hoc super-resolution models to generate high-resolution images. Furthermore, GAN- and diffusion-based approaches introduce stochasticity into generated stains which, although beneficial for visual realism in natural images, can lead to hallucinations and structural distortions that affect the accuracy and reliability required for clinical use. We propose IMPLICITSTAINER, a deterministic framework that reformulates virtual staining as a continuous pixel-level translation problem. In contrast to existing patch-based approaches, IMPLICITSTAINER formulates image translation as a continuous spatial mapping using neural implicit deep learning models. Each target-domain (IHC) pixel is predicted from a high-dimensional embedding of the corresponding source-domain H&E pixel, its local spatial neighborhood, and explicit coordinate information. IMPLICITSTAINER enables resolution-agnostic inference, improves robustness in low-data regimes, and yields deterministic, reproducible outputs. Across more than twenty baselines, IMPLICITSTAINER achieves SOTA performance on virtual staining tasks, including IHC and mIF.