Supply chain forecasting models degrade over time as real-world conditions change. Promotions shift, consumer preferences evolve, and supply disruptions alter demand patterns, causing what is known as concept drift. This silent degradation leads to stockouts or excess inventory without triggering any system warnings. Current industry practice relies on manual monitoring and scheduled retraining every 3-6 months, which wastes computational resources during stable periods while missing rapid drift events. Existing academic methods focus narrowly on drift detection without addressing diagnosis or remediation, and they ignore the hierarchical structure inherent in supply chain data. What retailers need is an end-to-end system that detects drift early, explains its root causes, and automatically corrects affected models. We propose DriftGuard, a five-module framework that addresses the complete drift lifecycle. The system combines an ensemble of four complementary detection methods, namely error-based monitoring, statistical tests, autoencoder anomaly detection, and Cumulative Sum (CUSUM) change-point analysis, with hierarchical propagation analysis to identify exactly where drift occurs across product lines. Once detected, Shapley Additive Explanations (SHAP) analysis diagnoses the root causes, and a cost-aware retraining strategy selectively updates only the most affected models. Evaluated on over 30,000 time series from the M5 retail dataset, DriftGuard achieves 97.8% detection recall within 4.2 days and delivers up to 417 return on investment through targeted remediation.