The rapid advancement of generative adversarial networks (GANs) and diffusion models has enabled the creation of highly realistic deepfake content, posing significant threats to digital trust across audio-visual domains. While unimodal detection methods have shown progress in identifying synthetic media, their inability to leverage cross-modal correlations and precisely localize forged segments limits their practicality against sophisticated, fine-grained manipulations. To address this, we introduce a multi-modal deepfake detection and localization framework based on a Feature Pyramid-Transformer (FPN-Transformer), addressing critical gaps in cross-modal generalization and temporal boundary regression. The proposed approach utilizes pre-trained self-supervised models (WavLM for audio, CLIP for video) to extract hierarchical temporal features. A multi-scale feature pyramid is constructed through R-TLM blocks with localized attention mechanisms, enabling joint analysis of cross-context temporal dependencies. The dual-branch prediction head simultaneously predicts forgery probabilities and refines temporal offsets of manipulated segments, achieving frame-level localization precision. We evaluate our approach on the test set of the IJCAI'25 DDL-AV benchmark, showing a good performance with a final score of 0.7535 for cross-modal deepfake detection and localization in challenging environments. Experimental results confirm the effectiveness of our approach and provide a novel way for generalized deepfake detection. Our code is available at https://github.com/Zig-HS/MM-DDL