Polycystic Ovary Syndrome (PCOS) is the most familiar endocrine illness in women of reproductive age. Many Bangladeshi women suffer from PCOS disease in their older age. The aim of our research is to identify effective vision-based medical image analysis techniques and evaluate hybrid models for the accurate detection of PCOS. We introduced two novel hybrid models combining convolutional and transformer-based approaches. The training and testing data were organized into two categories: "infected" (PCOS-positive) and "noninfected" (healthy ovaries). In the initial stage, our first hybrid model, 'DenConST' (integrating DenseNet121, Swin Transformer, and ConvNeXt), achieved 85.69% accuracy. The final optimized model, 'DenConREST' (incorporating Swin Transformer, ConvNeXt, DenseNet121, ResNet18, and EfficientNetV2), demonstrated superior performance with 98.23% accuracy. Among all evaluated models, DenConREST showed the best performance. This research highlights an efficient solution for PCOS detection from ultrasound images, significantly improving diagnostic accuracy while reducing detection errors.