This thesis presents methods and datasets to investigate cartographic heritage on a large scale and from a cultural perspective. Heritage institutions worldwide have digitized more than one million maps, and automated techniques now enable large-scale recognition and extraction of map content. Yet these methods have engaged little with the history of cartography, or the view that maps are semantic-symbolic systems, and cultural objects reflecting political and epistemic expectations. This work leverages a diverse corpus of 771,561 map records and 99,715 digitized images aggregated from 38 digital catalogs. After normalization, the dataset includes 236,925 contributors and spans six centuries, from 1492 to 1948. These data make it possible to chart geographic structures and the global chronology of map publication. The spatial focus of cartography is analyzed in relation to political dynamics, evidencing links between Atlantic maritime charting, the triangular trade, and colonial expansion. Further results document the progression of national, domestic focus and the impact of military conflicts on publication volumes. The research introduces semantic segmentation techniques and object detection models for the generic recognition of land classes and cartographic signs, trained on annotated data and synthetic images. The analysis of land classes shows that maps are designed images whose framing and composition emphasize features through centering and semantic symmetries. The study of cartographic figuration encodes 63 M signs and 25 M fragments into a latent visual space, revealing figurative shifts such as the replacement of relief hachures by terrain contours and showing that signs tend to form locally consistent systems. Analyses of collaboration and diffusion highlight the role of legitimacy, larger actors, and major cities in the spread of figurative norms and semiotic cultures.