Use case

Example prompt

Prompt template

Choosing the right diagnostic tests

I am a hospitalist seeing a 62-year-old man with diabetes and chronic kidney disease who presents to the emergency department with fever, shortness of breath, and new confusion.

Based on this presentation, outline a focused diagnostic workup and test selection, including labs, imaging, and microbiology, to evaluate for sepsis and possible pneumonia, and explain how the results would guide initial management in an acute care hospital setting.

I am a [clinical role, e.g., hospitalist, emergency physician, ICU fellow, NP, PA] caring for a [age]-year-old [gender] patient with [key past medical conditions] who presents with [chief complaint(s)] and [key acute symptoms or signs] in a [care setting, e.g., emergency department, ICU]. 

Based on this presentation, provide a focused diagnostic workup and test selection using [diagnostic methods, e.g., labs, imaging, microbiology] to evaluate for [suspected condition(s), e.g., sepsis, pneumonia, PE, stroke], and explain how the results would guide [initial management, triage, or treatment decisions] in a [clinical setting].

Working through the differential

I am a clinician conducting a routine clinical assessment of a 28-year-old woman presenting with unilateral knee discomfort, intermittent calf tightness, and chest wall soreness after recent prolonged travel and increased physical activity. 

Generate a prioritized differential diagnosis and explain how patellofemoral pain syndrome can be distinguished from muscle strain, costochondritis, and stress-related symptoms using history, physical examination, and basic diagnostic evaluation.

I am a [clinical role, e.g., emergency physician, hospitalist, urgent care PA] evaluating a [age]-year-old [gender] with [chief complaint] and [key symptoms or exam findings] in the [care setting].

Generate a prioritized differential diagnosis for this presentation. For each diagnosis, explain what features of the history, exam, or initial tests would support or argue against it.

Then explain how to distinguish [primary suspected condition] from [alternative diagnosis #1], [alternative diagnosis #2], and [alternative diagnosis #3] using bedside evaluation, labs, and imaging.

Putting together a plan

I am a hospitalist managing a 74-year-old woman admitted with decompensated heart failure and worsening kidney function. Provide a problem-based assessment and plan covering volume management, medication adjustments, and discharge planning.

I am a [clinical role, e.g., hospitalist, ICU attending, NP, PA] managing a [age]-year-old [gender] admitted with [primary diagnosis] and [key complicating problems].

Create a problem-based assessment and plan that includes:

The pathophysiology driving each active problem

Diagnostics to trend or follow

Therapeutic plan (medications, fluids, procedures, monitoring)

Disposition and discharge planning

Highlight how [comorbidity or complication] affects management and what would trigger escalation or de-escalation of care.

Documenting the patient encounter

I am a pediatrician seeing a 3-year-old boy with fever, cough, and wheezing. Write a concise but thorough clinical note for suspected viral bronchiolitis, including history, exam, assessment, and plan.

Format it the way it would appear in a real chart.

I am a [clinical role, e.g., pediatrician, family medicine physician, resident] seeing a [age]-year-old [gender] with [chief complaint] and [key symptoms] in the [clinic / ED / hospital].

Write a concise but thorough clinical note including:

History of present illness

Relevant past history and medications

Focused physical exam

Assessment with differential

Plan (diagnostics, treatment, and follow-up)

Format it the way it would appear in a real chart.

Counseling the patient and setting next steps

I am an endocrinologist counseling a 60-year-old woman newly diagnosed with type 2 diabetes. Write patient-friendly after-visit instructions covering medications, diet, glucose monitoring, and when to seek care. 

I am a [clinical role, e.g., endocrinologist, primary care physician, nurse practitioner] counseling a [age]-year-old [gender] with [diagnosis].

Write patient-friendly after-visit instructions that explain:

What the condition means

How [medications] should be taken

Key diet, lifestyle, and monitoring recommendations

Red-flag symptoms that should prompt urgent care

Use clear, non-technical language appropriate for a [health-literacy level] patient.

Safely transitioning care

I am a hospital discharge planner coordinating care for a 72-year-old woman recovering from a hip fracture. Outline how you would communicate key issues to home health, physical therapy, and the primary care physician.

I am a [clinical role, e.g., hospital discharge planner, hospitalist, case manager] coordinating care for a [age]-year-old [gender] being discharged after [hospitalization or condition].

Outline the key information that must be communicated to:

[receiving provider, e.g., primary care physician]

[home health or rehab service]

[specialist, if applicable]

Include active problems, medications, pending tests, functional status, and follow-up needs, formatted as a clear handoff summary.

Checking against the evidence

I am a cardiologist reviewing care for a 65-year-old man with new-onset atrial fibrillation. 

Summarize the current guideline-based recommendations for anticoagulation, rate versus rhythm control, and stroke prevention as they apply to this patient.

I am a [clinical role, e.g., cardiologist, pulmonologist, hospitalist] reviewing the care of a [age]-year-old [gender] with [condition] and [key comorbidities].

Summarize the current guideline-based recommendations for:

Diagnosis and risk stratification

First-line and second-line therapies

Prevention of complications

Then explain how these guidelines apply to this specific patient given [relevant risk factors or constraints].

Retrieving and applying clinical references

I am a neurologist following a 79-year-old patient who had an ischemic stroke 2 years ago with minimal residual deficits. At his most recent visit, he reported memory decline, including losing his phone, and has become more irritable. His functional status in daily activities is mostly preserved. Should these symptoms raise suspicion for dementia, or are they more consistent with normal age-related cognitive changes? Provide a differential diagnosis and explain why it’s likely or not.

I am a [clinical role/specialty, e.g., neurologist, geriatrician, PCP] following a [age]-year-old [gender] patient who had [index neurologic event/condition, e.g., ischemic stroke/TIA/ICH] [timeframe, e.g., 2 years] ago with [degree of residual deficits, e.g., minimal residual deficits / moderate aphasia / mild hemiparesis]. 

At [his/her/their] most recent visit, [he/she/they] reported [cognitive concern, e.g., memory decline], including [example, e.g., losing phone/missed appointments/repeating questions], and has become [behavior or mood change, e.g., more irritable / apathetic / anxious]. [His/her/their] functional status in daily activities is [mostly preserved / mildly impaired / declining]. Should these symptoms raise suspicion for [condition, e.g., dementia / vascular cognitive impairment / Alzheimer’s disease], or are they more consistent with [normal age-related cognitive changes]? Provide a differential diagnosis and explain why it’s likely or not.

Using your system to guide care

Summarize the recommended initial evaluation for new cognitive concerns in an older adult with prior ischemic stroke. Use our organization’s approved pathway if available and link to the relevant sections. Include key red flags, the focused history/exam (including collateral and meds), recommended screening tool(s), baseline labs, and when imaging is indicated.

Summarize the recommended initial evaluation for [clinical problem, e.g., new cognitive concerns / new weakness / unexplained weight loss] in a [age]-year-old [gender] with [relevant history, e.g., prior ischemic stroke, heart failure, diabetes]. 

Use our organization’s [approved pathway / local guideline / service-line protocol] if available and link to the relevant section or document. 

Include key red flags, the focused history and exam (including [collateral sources, meds, or risk factors]), recommended screening tool(s), baseline labs, and when imaging [or specialist referral] is indicated.