Occupant comfort and grid-aware energy efficiency are competing objectives whose joint optimization depends critically on how reward functions are specified in deep reinforcement learning (DRL) controllers for buildings. Yet reward design remains largely ad hoc: comfort terms are either hand-tuned heuristics or simple temperature-deviation proxies without explicit grounding in thermal-comfort physics. We present PIRS (Physics-Informed Reward Shaping), which replaces these ad-hoc comfort proxies with the ISO 7730 Predicted Mean Vote (PMV) formulation inside a weighted multi-objective reward for Soft Actor-Critic (SAC). By anchoring the comfort signal in the ISO 7730 PMV formulation, PIRS improves reward interpretability and provides a standards-grounded comfort proxy without changing any other component of the learning pipeline. We evaluate PIRS in CityLearn v2.1.2 (challenge 2022 phase 1) with a central SAC agent trained for 50k steps over five random seeds, and compare against a rule-based controller (RBC), a manually engineered reward (E2), an energy-only reward (E3), and a naive temperature-deviation comfort reward (E4). District-level key performance indicators (KPIs), reported as ratios versus RBC, show that PIRS attains cost, carbon, and electricity metrics on par with the manual baseline while substantially outperforming non-physics-grounded designs -- particularly on load ramping (1.78x vs. ~2.4x RBC) and daily peak demand. All DRL policies remain above RBC at this training budget; we interpret this gap honestly and position PIRS as an interpretable, standards-aligned foundation for reward design rather than a claim of dominance over classical control at limited compute.