Mixed-integer programming (MIP) research is both mathematically sophisticated and engineering-intensive: testing an algorithmic hypothesis within a branch-and-cut solver requires substantial implementation, debugging, tuning, and large-scale benchmarking. We propose an agentic MIP research framework that shortens this feedback loop by embedding LLM agents into a solver-aware harness for generating, verifying, and evaluating plugins for the open-source solver SCIP. Propagation methods play a central role in accelerating MIP solving by exploiting global constraints. We instantiate our framework on the semantic lifting of MIP formulations into global constraints and the automatic construction of propagation-only SCIP constraint handlers. On the MIPLIB 2017 benchmark set, the framework successfully recovers global constraint structures from constraint programming and generates executable constraint detectors and propagation-only constraint handlers. Furthermore, the framework naturally extends to in-context learning within a sandboxed environment, enabling agents not only to tune and debug generated constraint handlers on real instances, but also to explore global constraint patterns in MIP problems and discover novel propagation strategies not yet implemented in SCIP. This framework allows us to systematically distinguish meaningful algorithmic improvements from low-value or overly costly candidates: the novel propagation methods successfully solved five additional instances within the explored benchmark. Overall, this framework demonstrates that LLM agents can autonomously navigate the complex MIP research loop, paving the way for a more automated solver development process.