Developing effective, domain-specific educational support systems is central to advancing AI in education. Although large language models (LLMs) demonstrate remarkable capabilities, they face significant limitations in specialized educational applications, including hallucinations, limited knowledge updates, and lack of domain expertise. Fine-tuning requires complete model retraining, creating substantial computational overhead, while general-purpose LLMs often provide inaccurate responses in specialized contexts due to reliance on generalized training data. To address this, we propose ARIA (Adaptive Retrieval Intelligence Assistant), a Retrieval-Augmented Generation (RAG) framework for creating intelligent teaching assistants across university-level courses. ARIA leverages a multimodal content extraction pipeline combining Docling for structured document analysis, Nougat for mathematical formula recognition, and GPT-4 Vision API for diagram interpretation, with the e5-large-v2 embedding model for high semantic performance and low latency. This enables accurate processing of complex educational materials while maintaining pedagogical consistency through engineered prompts and response controls. We evaluate ARIA using lecture material from Statics and Mechanics of Materials, a sophomore-level civil engineering course at Johns Hopkins University, benchmarking against ChatGPT-5. Results demonstrate 97.5% accuracy in domain-specific question filtering and superior pedagogical performance. ARIA correctly answered all 20 relevant course questions while rejecting 58 of 60 non-relevant queries, achieving 90.9% precision, 100% recall, and 4.89/5.0 average response quality. These findings demonstrate that ARIA's course-agnostic architecture represents a scalable framework for domain-specific educational AI deployment.