It is increasingly recognized that human annotators do not always agree, and such disagreement is inherent in many annotation tasks. However, not all instances in a given task elicit the same degree of opinion divergence. In this paper, we investigate annotation variation patterns in graded human ratings for inappropriate languages, including offensive language, hate speech, and toxic language perception. We examine whether the degree of annotation disagreement can be predicted from textual features. We further propose the Opposition Index, a metric that quantifies perspective opposition among annotators on a given item, and investigate the predictability of instances with potentially opposing human opinions. Our results show a moderate positive correlation between estimated and observed annotation variance. We find that two approaches achieve comparable performance in variance prediction: directly predicting the variance value and estimating it from predicted annotation distributions. Our results on opposition perspective prediction show that items with high opposition index values are more difficult to predict and are often underestimated by models.