























Large language models used for clinical abstraction are sensitive to prompt wording, yet most work treats prompts as fixed and studies uncertainty in isolation. We argue these should be treated jointly. Across two clinical tasks (MedAlign applicability/correctness and MS subtype abstraction) and multiple open and proprietary models, we measure prompt sensitivity via flip rates and relate it to calibration and selective prediction. We find that higher accuracy does not guarantee prompt stability, and that models can appear well-calibrated yet remain fragile to paraphrases. We propose a dual-objective prompt optimization loop that jointly targets accuracy and stability, showing that explicitly including a stability term reduces flip rates across tasks and models, sometimes at modest accuracy cost. Our results suggest prompt sensitivity should be an explicit objective when validating clinical LLM systems.
此内容由惯性聚合(RSS阅读器)自动聚合整理,仅供阅读参考。 原文来自 — 版权归原作者所有。