Large Language Models (LLMs) rely on Knowledge Editing (KE) to maintain temporal validity, yet real-world knowledge is inherently n-ary. We demonstrate that in non-stationary environments, sequential updates to complex relations induce N-ary Structural Drift, a phenomenon where the binary reification of n-ary events into triples fractures relational atomicity. This precipitates Structure-Conditioned Knowledge Transfer Failure, a systematic mis-grounding of the retriever frequently misdiagnosed as parametric hallucination. To tackle this, we propose HyperPatch, a parameter-preserving framework that reformulates sequential KE as a stability problem over hypergraph manifolds. HyperPatch preserves event integrity through three phases: (i) Structural Prior Initialization, establishing a topology-aware embedding space via contrastive learning on a Hypergraph Neural Network (HGNN) to capture high-order correlations; (ii) Sequential Topology Editing, utilizing a dual-stage mechanism that employs SimHash-based Topological Alignment for rapid conflict resolution and Topological LoRA Adaptation to track drift without backbone retraining; and (iii) Structure-Conditioned Reasoning, which integrates globally consistent evidence from fused linguistic and structural manifolds. On the MQuAKE-CF and MQuAKE-T benchmarks, HyperPatch achieves relative gains in Hop-wise Accuracy (H-Acc) of 96.24% and 21.06% over the strongest baseline, respectively. Further ablations demonstrate superior reliability under continuous n-ary update streams, whereas the standard KG-based variant suffers H-Acc collapses of up to 88.3% due to structural misalignment.