Large language models (LLMs) have demonstrated strong performance in general-purpose machine translation, but their effectiveness in complex, domain-sensitive translation tasks remains underexplored. Recent advancements in Large Reasoning Models (LRMs), raise the question of whether structured reasoning can enhance translation quality across diverse domains. In this work, we compare the performance of LRMs with traditional LLMs across 15 representative domains and four translation directions. Our evaluation considers various factors, including task difficulty, input length, and terminology density. We use a combination of automatic metrics and an enhanced MQM-based evaluation hierarchy to assess translation quality. Our findings show that LRMs consistently outperform traditional LLMs in semantically complex domains, especially in long-text and high-difficulty translation scenarios. Moreover, domain-adaptive prompting strategies further improve performance by better leveraging the reasoning capabilities of LRMs. These results highlight the potential of structured reasoning in MDMT tasks and provide valuable insights for optimizing translation systems in domain-sensitive contexts.