This study evaluates fine-tuning strategies for text classification using the DistilBERT model, specifically the distilbert-base-uncased-finetuned-sst-2-english variant. Through structured experiments, we examine the influence of hyperparameters such as learning rate, batch size, and epochs on accuracy, F1-score, and loss. Polynomial regression analyses capture foundational and incremental impacts of these hyperparameters, focusing on fine-tuning adjustments relative to a baseline model. Results reveal variability in metrics due to hyperparameter configurations, showing trade-offs among performance metrics. For example, a higher learning rate reduces loss in relative analysis (p=0.027) but challenges accuracy improvements. Meanwhile, batch size significantly impacts accuracy and F1-score in absolute regression (p=0.028 and p=0.005) but has limited influence on loss optimization (p=0.170). The interaction between epochs and batch size maximizes F1-score (p=0.001), underscoring the importance of hyperparameter interplay. These findings highlight the need for fine-tuning strategies addressing non-linear hyperparameter interactions to balance performance across metrics. Such variability and metric trade-offs are relevant for tasks beyond text classification, including NLP and computer vision. This analysis informs fine-tuning strategies for large language models and promotes adaptive designs for broader model applicability.