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cs.CL updates on arXiv.org

Playing Along: Learning a Double-Agent Defender for Belief Steering via Theory of Mind RPA-Check: A Multi-Stage Automated Framework for Evaluating Dynamic LLM-based Role-Playing Agents A Triadic Suffix Tokenization Scheme for Numerical Reasoning Hidden Measurement Error in LLM Pipelines Distorts Annotation, Evaluation, and Benchmarking Synthius-Mem: Brain-Inspired Hallucination-Resistant Persona Memory Achieving 94.4% Memory Accuracy and 99.6% Adversarial Robustness on LoCoMo Time is Not a Label: Continuous Phase Rotation for Temporal Knowledge Graphs and Agentic Memory NovBench: Evaluating Large Language Models on Academic Paper Novelty Assessment Policy Split: Incentivizing Dual-Mode Exploration in LLM Reinforcement with Dual-Mode Entropy Regularization METER: Evaluating Multi-Level Contextual Causal Reasoning in Large Language Models Think Before you Write: QA-Guided Reasoning for Character Descriptions in Books METRO: Towards Strategy Induction from Expert Dialogue Transcripts for Non-collaborative Dialogues Retrieval as Generation: A Unified Framework with Self-Triggered Information Planning Do LLMs Know Tool Irrelevance? Demystifying Structural Alignment Bias in Tool Invocations Enhancing Multimodal Large Language Models for Ancient Chinese Character Evolution Analysis via Glyph-Driven Fine-Tuning Polyglot Teachers: Evaluating Language Models for Multilingual Synthetic Data Generation Exploring Knowledge Conflicts for Faithful LLM Reasoning: Benchmark and Method CocoaBench: Evaluating Unified Digital Agents in the Wild MathAgent: Adversarial Evolution of Constraint Graphs for Mathematical Reasoning Data Synthesis Evaluating Memory Capability in Continuous Lifelog Scenario How Robust Are Large Language Models for Clinical Numeracy? An Empirical Study on Numerical Reasoning Abilities in Clinical Contexts Efficient Training for Cross-lingual Speech Language Models Shared Emotion Geometry Across Small Language Models: A Cross-Architecture Study of Representation, Behavior, and Methodological Confounds A Systematic Analysis of the Impact of Persona Steering on LLM Capabilities Uncertainty-Aware Web-Conditioned Scientific Fact-Checking When Valid Signals Fail: Regime Boundaries Between LLM Features and RL Trading Policies When Verification Fails: How Compositionally Infeasible Claims Escape Rejection Mem$^2$Evolve: Towards Self-Evolving Agents via Co-Evolutionary Capability Expansion and Experience Distillation AOP-Smart: A RAG-Enhanced Large Language Model Framework for Adverse Outcome Pathway Analysis OccuBench: Evaluating AI Agents on Real-World Professional Tasks via Language Environment Simulation Advancing Polish Language Modeling through Tokenizer Optimization in the Bielik v3 7B and 11B Series TInR: Exploring Tool-Internalized Reasoning in Large Language Models Do BERT Embeddings Encode Narrative Dimensions? A Token-Level Probing Analysis of Time, Space, Causality, and Character in Fiction Generating Multiple-Choice Knowledge Questions with Interpretable Difficulty Estimation using Knowledge Graphs and Large Language Models Deep-Reporter: Deep Research for Grounded Multimodal Long-Form Generation BlasBench: An Open Benchmark for Irish Speech Recognition Too Nice to Tell the Truth: Quantifying Agreeableness-Driven Sycophancy in Role-Playing Language Models Learning and Enforcing Context-Sensitive Control for LLMs HeceTokenizer: A Syllable-Based Tokenization Approach for Turkish Retrieval Efficient Process Reward Modeling via Contrastive Mutual Information Computational Lesions in Multilingual Language Models Separate Shared and Language-specific Brain Alignment Bridging Linguistic Gaps: Cross-Lingual Mapping in Pre-Training and Dataset for Enhanced Multilingual LLM Performance Knowing What to Stress: A Discourse-Conditioned Text-to-Speech Benchmark Early Decisions Matter: Proximity Bias and Initial Trajectory Shaping in Non-Autoregressive Diffusion Language Models LLMs Should Incorporate Explicit Mechanisms for Human Empathy ReFEree: Reference-Free and Fine-Grained Method for Evaluating Factual Consistency in Real-World Code Summarization Structure-Grounded Knowledge Retrieval via Code Dependencies for Multi-Step Data Reasoning From Query to Counsel: Structured Reasoning with a Multi-Agent Framework and Dataset for Legal Consultation Dynamic Adaptive Attention and Supervised Contrastive Learning: A Novel Hybrid Framework for Text Sentiment Classification EviCare: Enhancing Diagnosis Prediction with Deep Model-Guided Evidence for In-Context Reasoning NOSE: Neural Olfactory-Semantic Embedding with Tri-Modal Orthogonal Contrastive Learning Instruction Data Selection via Answer Divergence CodaRAG: Connecting the Dots with Associativity Inspired by Complementary Learning Turing or Cantor: That is the Question LASQ: A Low-resource Aspect-based Sentiment Quadruple Extraction Dataset NameBERT: Scaling Name-Based Nationality Classification with LLM-Augmented Open Academic Data BLUEmed: Retrieval-Augmented Multi-Agent Debate for Clinical Error Detection A Structured Clustering Approach for Inducing Media Narratives Adaptive Multi-Expert Reasoning via Difficulty-Aware Routing and Uncertainty-Guided Aggregation Comparative Analysis of Large Language Models in Healthcare CodeComp: Structural KV Cache Compression for Agentic Coding Relational Probing: LM-to-Graph Adaptation for Financial Prediction FAITH: Factuality Alignment through Integrating Trustworthiness and Honestness ODUTQA-MDC: A Task for Open-Domain Underspecified Tabular QA with Multi-turn Dialogue-based Clarification Nationality encoding in language model hidden states: Probing culturally differentiated representations in persona-conditioned academic text Think in Sentences: Explicit Sentence Boundaries Enhance Language Model's Capabilities Training-Free Cross-Lingual Dysarthria Severity Assessment via Phonological Subspace Analysis in Self-Supervised Speech Representations CircuitSynth: Reliable Synthetic Data Generation Who Wrote This Line? Evaluating the Detection of LLM-Generated Classical Chinese Poetry SEPTQ: A Simple and Effective Post-Training Quantization Paradigm for Large Language Models Why Supervised Fine-Tuning Fails to Learn: A Systematic Study of Incomplete Learning in Large Language Models Reason Only When Needed: Efficient Generative Reward Modeling via Model-Internal Uncertainty ASPIRin: Action Space Projection for Interactivity-Optimized Reinforcement Learning in Full-Duplex Speech Language Models Mirroring Minds: Asymmetric Linguistic Accommodation and Diagnostic Identity in ADHD and Autism Reddit Communities Computational Implementation of a Model of Category-Theoretic Metaphor Comprehension CoSToM:Causal-oriented Steering for Intrinsic Theory-of-Mind Alignment in Large Language Models Weird Generalization is Weirdly Brittle Human vs. Machine Deception: Distinguishing AI-Generated and Human-Written Fake News Using Ensemble Learning Should We be Pedantic About Reasoning Errors in Machine Translation? Simulating Organized Group Behavior: New Framework, Benchmark, and Analysis Spoiler Alert: Narrative Forecasting as a Metric for Tension in LLM Storytelling Claim2Vec: Embedding Fact-Check Claims for Multilingual Similarity and Clustering GIANTS: Generative Insight Anticipation from Scientific Literature Many-Tier Instruction Hierarchy in LLM Agents Interactive ASR: Towards Human-Like Interaction and Semantic Coherence Evaluation for Agentic Speech Recognition Regime-Conditional Retrieval: Theory and a Transferable Router for Two-Hop QA ASTRA: Adaptive Semantic Tree Reasoning Architecture for Complex Table Question Answering Revisiting the Capacity Gap in Chain-of-Thought Distillation from a Practical Perspective Dictionary-Aligned Concept Control for Safeguarding Multimodal LLMs $p1$: Better Prompt Optimization with Fewer Prompts Every Response Counts: Quantifying Uncertainty of LLM-based Multi-Agent Systems through Tensor Decomposition Skip-Connected Policy Optimization for Implicit Advantage PRAGMA: Revolut Foundation Model Linear Representations of Hierarchical Concepts in Language Models Generating High Quality Synthetic Data for Dutch Medical Conversations HumorGen: Cognitive Synergy for Humor Generation in Large Language Models via Persona-Based Distillation Toward Generalized Cross-Lingual Hateful Language Detection with Web-Scale Data and Ensemble LLM Annotations Self-Calibrating Language Models via Test-Time Discriminative Distillation Re-Mask and Redirect: Exploiting Denoising Irreversibility in Diffusion Language Models H-AdminSim: A Multi-Agent Simulator for Realistic Hospital Administrative Workflows with FHIR Integration Reasoning Models Will Sometimes Lie About Their Reasoning
Real-world validation of a multimodal LLM-powered pipeline for High-Accuracy Clinical Trial Patient Matching leveraging EHR data
2025-03-20 · via cs.CL updates on arXiv.org

Background: Patient recruitment in clinical trials is hindered by complex eligibility criteria and labor-intensive chart reviews. Prior research using text-only models have struggled to address this problem in a reliable and scalable way due to (1) limited reasoning capabilities, (2) information loss from converting visual records to text, and (3) lack of a generic EHR integration to extract patient data. Methods: We introduce a broadly applicable, integration-free, LLM-powered pipeline that automates patient-trial matching using unprocessed documents extracted from EHRs. Our approach leverages (1) the new reasoning-LLM paradigm, enabling the assessment of even the most complex criteria, (2) visual capabilities of latest LLMs to interpret medical records without lossy image-to-text conversions, and (3) multimodal embeddings for efficient medical record search. The pipeline was validated on the n2c2 2018 cohort selection dataset (288 diabetic patients) and a real-world dataset composed of 485 patients from 30 different sites matched against 36 diverse trials. Results: On the n2c2 dataset, our method achieved a new state-of-the-art criterion-level accuracy of 93\%. In real-world trials, the pipeline yielded an accuracy of 87\%, undermined by the difficulty to replicate human decision-making when medical records lack sufficient information. Nevertheless, users were able to review overall eligibility in under 9 minutes per patient on average, representing an 80\% improvement over traditional manual chart reviews. Conclusion: This pipeline demonstrates robust performance in clinical trial patient matching without requiring custom integration with site systems or trial-specific tailoring, thereby enabling scalable deployment across sites seeking to leverage AI for patient matching.