Writing systems are cultural replicators whose evolution has never been studied quantitatively at global scale. We compile the Global Script Database (GSD): 300 writing and notation systems, 50 binary structural characters, and 259 phylogenetic edges spanning 5,400 years. Applying four methods -- phenetics, cladistics, Bayesian inference, and neural network clustering -- we find that scripts exhibit a detectable molecular clock. The best-fitting model (Mk+Gamma strict clock) yields a substitution rate of q = 0.226 substitutions/character/millennium (95% CI: 0.034-1.22; Delta BIC = -4.1 versus relaxed clock; Delta BIC = -1,364.7 versus Mk without rate variation). Political interventions break this clock: deviation from expected divergence times correlates with intervention intensity (Spearman rho = 0.556, p < 10^{-4}), and per-character rate analysis reveals that intervention selectively rewrites deep structural features rather than merely accelerating change (rate profile correlation rho = 0.320). We identify 30 major script replacement events and rank their destructive impact. A ceiling effect suppresses independent invention wherever writing already exists (Fisher's exact OR = 0.054, p < 10^{-6}), and colonial contact predicts script extinction (Cox HR = 5.25, p = 0.0006). The Spanish Empire extinguished the most scripts (6 of 12 contacted, 50%), followed by the Empire of Japan (3 of 9, 33.3%). Feature coding was validated by inter-rater reliability testing with two independent human coders (Cohen's kappa = 0.877; human-LLM kappa = 0.929; Fleiss' kappa = 0.911).