The development of Multimodal Large Language Models (MLLMs) has seen significant advancements with increasing demands in various fields (e.g., multimodal agents, embodied intelligence). While model-driven approaches attempt to enhance MLLMs capabilities through diverse architectures, the gains have become increasingly marginal. Conversely, data-driven methods, which scale up image-text instruction data, are more effective but face limited data diversity and complexity challenges. The absence of high-quality data constitutes a significant development barrier for MLLMs. To address the data quality bottleneck, we propose MMEvol, a novel multimodal instruction data evolution framework. This framework iteratively improve data quality through a refined combination of fine-grained perception, cognitive reasoning, and interaction evolution, generating a more complex and diverse image-text instruction dataset that empowers MLLMs with enhanced capabilities. Beginning with an initial set of instructions, SEED-163K, we utilize MMEvol to systematically broaden the diversity of instruction types, extend visual reasoning steps to improve cognitive reasoning abilities, and thoroughly explore fine-grained information within images to enhance visual understanding and robustness. To comprehensively evaluate the effectiveness of our approach, we conduct extensive qualitative analysis and quantitative experiments across 13 vision-language tasks. Compared to baseline models trained with the initial seed data, the results demonstrate that our method achieves an average accuracy improvement of 3.1 percentage points. Furthermore, our approach reaches state-of-the-art (SOTA) performance in nine tasks using significantly less data compared to state-of-the-art models.