Improving air quality and addressing climate change relies on accurate understanding and analysis of air pollutant and greenhouse gas emissions. However, emission-related knowledge is often fragmented and highly specialized, while existing methods for accessing and compiling emissions data remain inefficient. These issues hinder the ability of non-experts to interpret emissions information, posing challenges to research and management. To address this, we present Emission-GPT, a knowledge-enhanced large language model agent tailored for the atmospheric emissions domain. Built on a curated knowledge base of over 10,000 documents (including standards, reports, guidebooks, and peer-reviewed literature), Emission-GPT integrates prompt engineering and question completion to support accurate domain-specific question answering. Emission-GPT also enables users to interactively analyze emissions data via natural language, such as querying and visualizing inventories, analyzing source contributions, and recommending emission factors for user-defined scenarios. A case study in Guangdong Province demonstrates that Emission-GPT can extract key insights--such as point source distributions and sectoral trends--directly from raw data with simple prompts. Its modular and extensible architecture facilitates automation of traditionally manual workflows, positioning Emission-GPT as a foundational tool for next-generation emission inventory development and scenario-based assessment.