可以先参考

http://www.tzwhx.com/newOperate/html/7/71/711/22426.html

需要注意的是，默认的配置没有绑定到任意IP地址和虚拟目录，经过测试，以下配置可以使用

 <sites>
            <site name="WebSite1" id="1" serverAutoStart="true">
                <application path="/" applicationPool="Clr2ClassicAppPool">
             <virtualDirectory path="/" physicalPath="你的网站物理目录\" />
                </application>
        <application path="/xtcrm" applicationPool="Clr2ClassicAppPool">
            <virtualDirectory path="/" physicalPath="你的应用程序物理目录" />
                </application>
                <bindings>
                    <binding protocol="http" bindingInformation=":80:" />
                </bindings>
            </site>
            <siteDefaults>
                <logFile logFormat="W3C" directory="%IIS_USER_HOME%\Logs" />
                <traceFailedRequestsLogging directory="%IIS_USER_HOME%\TraceLogFiles" enabled="true" maxLogFileSizeKB="1024" />
            </siteDefaults>
            <applicationDefaults applicationPool="Clr4IntegratedAppPool" />
            <virtualDirectoryDefaults allowSubDirConfig="true" />
        </sites>

然后将applicationhost.config 这个文件复制到你指定的目录

最后运行“iisexpress /config:你的applicationhost.config物理路径"