A wave of gun violence swept across Chicago as multiple shootings left six people dead and 28 others wounded.

The weekend's largest spree unfolded on Juneteenth, when a mass shooting in Chicago's Roseland neighborhood on the South Side left 13 people injured Friday night.

Chicago police said a red SUV pulled up to a large crowd in the 200 block of West 95th Street shortly after 11pm, and two people inside opened fire on those gathered, leaving 13 people injured, CBS News reported.

Mayor Brandon Johnson addressed the mass shooting while speaking at a Juneteenth Day of Action event on Saturday.

'Last night was another reminder of how much work we still have to do to protect the lives who have been impacted by gun violence,' he said. 

'As a father, as a husband, as a brother, as a cousin, just as a resident, it is heartbreaking. It's difficult to even digest and consume. There are too many families that have experienced loss in this city.'

The victims were between 14 and 70 years old. Mass violence erupted across the city beginning Thursday ahead of the extended holiday weekend. 

A 32-year-old man was killed when shots were fired from a vehicle near an alley in the 600 block of East 92nd Place on Thursday at 5.45pm. 

Later at 9.30pm, a 30-year-old man was struck in the foot by gunfire. He transported himself to Stroger Hospital and was listed in good condition. 

Around 11.30pm, officers found a 14-year-old boy suffering from multiple gunshot wounds in the 8000 block of South Carpenter Street. He later died. 

On Friday, 11 shootings were reported across Chicago, beginning as early as 4.30am and continuing until shortly after 11pm.

The day’s first victim was a 37-year-old man shot in a drive-by early in the morning. He is currently in stable condition. 

An 18-year-old male was later shot in the right wrist at 10.10am in the 6900 block of South Michigan Avenue and is in good condition. 

Just before 2pm, an unidentified male was shot in the chest and right arm while walking in the 600 block of East 80th Street and survived the attack. 

A 37-year-old man was injured in a shooting around 5pm inside an apartment in the 3800 block of West Maypole Avenue. He suffered a gunshot wound to the right leg and was in stable condition. 

Minutes later, at 5.14pm in the 11900 block of South Michigan Avenue, a 29-year-old man was standing near a sidewalk when an SUV pulled up and at least one person inside opened fire, striking him in the body and face. He later died. 

A 70-year-old man standing near the sidewalk was also struck by gunfire from the same vehicle, suffering a leg wound. Police later said he was in stable condition. 

Around 8.53pm in the 3700 block of West 30th Street, a 33-year-old man was found with multiple gunshot wounds and later died.

Roughly an hour later, two men, ages 26 and 28, were critically injured in the South Dobson Avenue area. Minutes after that, a 34-year-old man was found dead from a gunshot wound to the chest. 

Just after 11pm in the 6700 block of South Ada Street, a 32-year-old man was shot in the left leg and was listed in fair condition.

As of Saturday, six shootings were reported beginning as early as 12.15am, including one that killed a 37-year-old man who was struck in the neck. Five others were shot over the following hours at different locations and survived, some in drive-by attacks.

No arrests had been made as of Saturday night.