An ASP.NET setting has been detected that does not apply in Integrated managed pipeline mode.

解决方法有两个:

一个是在线程池中将其改成classic（经典模式）;

还有一种方法是在配置文件中添加一段：

<system.webServer> 
        <validation validateIntegratedModeConfiguration="false" /> 
</system.webServer>